No. You need an internet connection to use Synaptic Research. (This guarantees that you always have access to all your work, regardless of which computer you did the research on, and that you are seeing the latest product and data. It also ensures that any standards enforced by your compliance officer are applied to your research.)
However, the system should be more than acceptably fast over dial-up and mobile-phone connections as well as broadband. In addition, the software requires no installation and can therefore be used easily and safely from computers such as internet cafes and even clients’ own home computers.